Mass spectrometry is an analytical technique based on the separation of ionized molecules according to their mass-charge ratio in an electric field. Mass spectrometer consists of several successive parts for the introduction of the sample using separation chromatographic techniques (liquid LC or gaseous GC), the ionization of the molecules in the source (fragmentation by electron impact or chemical ionization), the acceleration and separation of ions formed into the analyzer (single or triple quadrupole filter) and the detection (electron multiplier) to obtain the mass spectrum to be analyzed
Capillary electrophoresis is a separation chromatographic method based on the differential migration of ionic species depending on their charge and frictional forces acting on them. The molecules are separated in a fused silica capillary with a small diameter immersed in a conductive fluid under the influence of a strong electric field (100 to 500 V / cm) applied to the ends of the capillary. Quantification was achieved by laser-Induced fluorescence detection (CE-LIF).