Neurocentre Magendie



Tél : / 33(0)5 57 57 40 59
Envoyer un email

-FRM PhD fellow (October 2017 - September 2018 ), University of Bordeaux
-Erasmus Mundus Joint PhD Fellow (October 2014- September 2017). University of Bordeaux, University of Zurich
-EMBO short term fellow (September 2016- November 2016), Brain Research Institute, University of Zurich
-Research Intern, Max-Plank Institute of Biological Cybernetics, Department of Computational Anatomy, Tuebingen, Germany (1st October 2013- 13 December 2013)
-MSc. Human Physiology, Department of Life Sciences, University of Calicut, India (August 2007- December 2009)
-BSc. Zoology from MES KVM college, Department of Zoology, University of Calicut, India (June 2003- March 2006)


-Teaching Assistant at Physiologisches Institute (Conductance of nerves), University of Zurich (Spring 2017)
-Teaching assistant in electrophysiology course (multielectrode optotetrode recordings) in summer school at the Brain research Institute, University of Zurich (December 7-14, 2016).
-Teaching Assistant at Physiologisches Institute (Heart-ECG Lab class), University of Zurich (Fall 2016)
- Lecturer in Physiology in Medical School of Nanchang University, Jianxi province, China from February 15- June 18, 2014.
- Assistant lecturer in Physiology in International medical and technological University, Dar Es Salaam, Tanzania from April 5, 2010 to September 23, 2013.
-Guest lecturer in Koyili College of nursing college, India from September 2009 to March 2010.

Expertise: Single cell patch clamp in vivo, Single cell electroporation in vivo, Juxtasomal recording in vivo, Stereotaxic injection, Immunohistochemistry, Neurolucida

7 publication(s) depuis Avril 2012:

Trier par

* equal contribution
Les IF indiqués ont été collectés par le Web of Sciences en

Objective: Study to elucidate the relation between depression, gender and blood groups. Methods: The study was prepared on 279 medical students of IMTU, who have spent more than four months in the medical school. A Performa for testing depression scale was given to the students. Blood groups and gender were analyzed. Results: It was evident that few blood groups like A and O shown significant prevalence of mild depression and group AB with severe depression. Females shown a high frequency of mild depression and males demonstrated an elevated severe depressed condition. Conclusion: The present study shows that blood groups, gender and depression scales are interconnected

06/2014 | Int. J. Pharm. Phytopharmacol. Res.
The Enormity of Total Serum Cholesterol Levels and the Scale of Awareness on Control and Management of Cholesterol in Diabetics in Zanzibar.
Ali Mohamed Mahmoud*, Narasimha Rao Bhoggireddy*, A-Bhaskaran A

Diabetes mellitus is an emerging global health problem. It is a chronic, non-communicable, and expensive public health disease. Lipid disorders are very common in both IDDM and NIDDM persons and the most common type of lipid abnormalities encountered in a subject with diabetes mellitus are elevated plasma levels of triglycerides, VLDL-C, LDL-C and decreased HDL-C. The objective of the present study was to determine the magnitude of total serum cholesterol level among diabetic patients and to assess the knowledge on how to control and manage the cholesterol levels. A total of 288 subjects aged between 18 years of age and above we re included in the study. A Performa was used to evaluate lifestyle characteristics and knowledge behind. Blood samples were collected and measured lipid profile levels. In this study the diabetic females fall in age group 38 years and above are showed high level of cholesterol than males. It also showed that, the high cholesterol level in diabetics w a s caused by shortage of awareness. This study will help the diabetics as to what extent to manage and control cholesterol levels. It has been suggested that education on effect of cholesterol levels and t h e i r ways of managing cholesterol should be provided to diabetics.

02/2014 | The Journal of Human disease
Studies on seroprevalence of Hepatitis B surface antigen among blood donors at blood transfusion center Zanzibar.
Said Nassor Rashid, NarasimhaRao Bhogireddy,Sivanageswararao Mekala, A-Bhaskaran A, Isaac Umapathy*, Alpana Verma*

Cross sectional studyon determination of the seroprevalence of Hepatitis B surface Antigen (HBsAg)among blood donors, at the Blood Bank Center Zanzibar was conducted. 384 blooddonors were used for this study. Out of 384 blood donors, 7 (1.82%) werepositive, which comes under the “low prevalence (<2%) zone” as per WorldHealth Organization (WHO) guidelines. Out of 384 blood donors, 372 (96.87%) weremales and 12 (3.12%) were females. The high seroprevalence of HBsAg wasobserved in age group of 18-25 years. Voluntary donors and male blood donorsshowed higher seropositivity. Almost nil seroprevalence was observed amongreplacement donors and female donors. Although Zanzibar has a low prevalence ofhepatitis B in blood donors but ensuring blood safety has a long way to go.

01/2014 | Asian J Pharm Clin Res   IF 0.6
Thyroid stimulating hormone and free thyroxine as an indication of thyroid dysfunction at pathology laboratory of mnazi mmoja hospital, Zanzibar.
Yussuf Ayoub Yussuf*, Narasimharao Bhogireddy*, Venkatarao Vulli, Alpana verma, A-Bhaskaran A

BACKGROUND: Iodine is a fundamental micronutrient intended for usual human growth and development. It is predictable that more than 1.6 billion people reside in iodine-deficient situations; however there are still some countries and areas where the prevalence of iodine-deficiency disorders is unknown. Iodine deficiency disorder (IDD) is major public health problem in many parts of the world as well as Zanzibar everywhere its consequence including thyroid dysfunction abnormalities, endemic goiter and cretinism. METHODS: In a cross-sectional study, based on laboratory investigation to find out the levels of free T4, freeT3 and thyroid stimulating hormone (TSH). All patient aged 10 and above suspected having thyroid. A total of 288 samples were collected from the patients suspected having a thyroid dysfunction and those samples were processed by automatic multi scan Elisa reader automated machine at clinical chemistry department of pathology laboratory MMH. RESULTS & CONCLUSION: This study shows lower levels of TSH in women are 26(9percent) and male are 9(3.1percent) and the higher levels are 20(7percent) and 12(4.1percent). The lower levels of fT3 in women are 11(4percent) and 3(1percent) in male and the high levels of fT3 in women are 78(27percent) and 31(11percent) in male. Lower levels of free T4 in women 10(3percent). High levels women are 117(41percent) and 44(15percent) in male. According to these results women had more thyroid dysfunction compare to males.

09/2013 | Int J Pharm Pharm Sci   IF 0.5
Gender correlated incidence of hypertension and body mass index in assorted age groups in Dar es Salaam.
MalligaElangovan, AlpanaVerma, I.Elangovan, Narasimharao Bhogireddy, A-Bhaskaran A

ABSTRACT Objective: Many developing countries are currently burdened by both under nutrition and rising rates of overweight and obesity. However, only a few reports are accessible from health workforce on recent trends and current epidemiology of obesity in Africa. Obesity has been renowned as a distinct best predictor of hypertension incidence, and is considered as a key cause of hypertension. Methods: We conducted a cross-sectional survey of 833 persons in an age group of 15-65 years in Dar-es-Salaam, Tanzania. The height, weight, and blood pressure (BP) of volunteers were recorded and mean BMIs determined. The findings were grouped into underweight, normal, over weight and obese based on BMI values. Hypertension was determined from measurements of blood pressure. After pooling of data the results were grouped according to gender across the age group and these were correlated with their blood pressure and BMI values. Results: When a Body Mass Index (BMI) comparison made between the genders females are exposed the uppermost, normal proportion of overweight/obese BMI (43.11%) than the male population (36.36%). Of the women, 15.59% and 29.05% of the men had hyper tension (&#8805;140/90 mmHg). We have distinguished a straight relation connecting hypertension and Overweight/ Obese BMI. A considerable association of hypertension and BMI to the genders was observed in the study. Conclusion: Present study reflects that there is a relationship among gender, hypertension and BMI. Usually, an event of hypertension is originated as the obesity and age increases but the current study revealed that the BMI and age were the significant determinants of hypertension across the human health resources. Therefore the result recommends, about the worry for the prevention of obesity and hypertension as a public health problem.

The anti-diabetic effect of aqueous extract of the leaves of Calycopteris floribunda (Combretaceae) was investigated in streptozotocin (STZ) induced diabetic rats. Diabetes was induced in rats by a single intraperitoneal injection of streptozotocin (40 mg / kg body weight). The test group received single dose of the extract (500 mg / kg body weight) daily for 10 days orally. The effect of the extract on the blood glucose and urine glucose was investigated. The present study shows that the Calycopteris floribunda leaves have a significant effect on hyperglycemia and glycosuria in diabetic rats. Further studies are required to elucidate the sites, constituents involved, as well as the cellular and molecular mechanism of actions of Calycopteris floribunda leaf extract.

04/2012 | IMTU Medical Journal
Prevalence of Cerebral Palsy in Children (Under Five) in and around Dar es Salaam.
Allen O. Kisanga, Malliga Elangovan, A-Bhaskaran A, Alpana Verma

Cerebral palsy (CP) is a non-progressive disorder of posture and movement due to brain damage/insult/lesion before birth, during delivery or in the perinatal period. It is a neurological disorder of childhood with significant medico-social implications. A retrospective hospital based cross sectional study was conducted to determine the prevalence and causes of cerebral palsy among children (under the age of five) attending orthopedic clinics and physiotherapy unit at CCBRT Hospital. Information was collected from registry books and patients files using a design table and then depicted on the prepared dummy tables for report. 232 cases male: 144; female: 88) met the inclusion criteria. Of these, 48 came from Kinondoni district of Dar-es-Salaam. Most of the cases were from 1 to 2 years old children. The males were affected most. The most common etiological factor encountered includes spastic form of cerebral palsy in 75% cases.About 86% of patients had delayed milestone as an associated condition. Most cases of cerebral palsy in Dar-es-Salaam were related to perinatal problems. Improved perinatal care may reduce the burden of cerebral palsy in the community. High rates of erratic and irregular followup by the parents of the affected children are also a cause for poor care of the affected children. The parents should also be motivated through education and explanations to improve the quality of care available to affected children.