Neurocentre Magendie

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Après l'obtention de son doctorat en neurosciences chez Giovanni Marsicano, en 2015 Tifany Desprez a choisi la voie de la communication scientifique, Bordeaux Neurocampus a bénéficié de son savoir faire pendant 2 mois (Mai-Juin). Pour Bordeaux Neurocampus , le LabEx BRAIN et l'Ecole des Neurosciences elle a réalisé avec maestria de nombreux supports graphiques, des opérations de communications, l'animation et le développement des réseaux sociaux, etc...
Des flyers Bordeaux Neurocampus, Ecole des neurosciences , des tee-shirt , des sacs en tissus floqués avec nos logos, des Kakemono-Roll-up, des marques pages, des stylos FBN sont disponibles pour vos déplacements dans les congrès au Rdc de l'Institut Magendie. Merci à Tifany pour son talent et son savoir-faire , nous lui souhaitons une belle réussite dans ce domaine




Hottopic
15/06/2016 12h00
Laurie ROBIN Laurie ROBIN from Marsicano's lab will give a presentation entitled "Astroglial CB1 receptors control memory via D-serine"


le mardi 7 juin prochain (accueil à partir de 8h30) à l’Espace Agora au domaine du Haut Carré à Talence. Merci de confirmer votre présence en vous inscrivant au moyen du lien http://doodle.com/poll/a4r4i38vg2g3ye3f


Présentations des membres du Neurocentre:
Arnau Busquets-Garcia (NCM - Eq Marsicano): "Role of CB1 receptors in mediated learning processes"

Sophie Tronel (NCM - Eq Abrous): "Role of adult hippocampal neurogenesis inspatial memory reconsolidation"





Séminaire
27/05/2016 11h30
Mike Murphy

Meeting room: Neurocentre Magendie Seminar room

from University of Cambridge will give a presentation entitled 'Mitochondrial superoxide production in ischaemia-reperfusion injury'

Invitant : Giovanni Marsicano, Giovanni Marsicano´s Lab / Neurocentre Magendie

Abstract :

Mitochondrial ROS have long been known to contribute to ischaemia-reperfusion (IR) injury in heart attack and stroke, but methods to stop this ROS production were limited. Over the past few years we have developed a mitochondria-targeted S-nitrosating agent, called MitoSNO, that we showed was effective in preventing ROS formation in IR injury with therapeutic implications. In addition, the protection by this compound suggested that ROS production in IR injury was mainly coming from complex I.
This led us to investigate the mechanism of the ROS production and using a metabolomic approach we found that the ROS production in IR injury came from the accumulation of citric acid cycle substrates during ischaemia that then drove mitochondrial ROS production by reverse electron transport at complex I during reperfusion.
This surprising mechanism led up to develop further new therapeutic approaches.



Séminaire
13/05/2016 11h30
Alberto Bacci

Meeting room: CGFB Seminar room

from ICM Paris (team leader / Equipe Inhibition synaptique et auto-modulation des microcircuits du cortex cérébral) will give a presentation entitled 'Long-term Plasticity of Neocortical GABAergic Synapses'

Invitant : Giovanni Marsicano, Neurocentre Magendie




Une organisation Guillaume Ferreira et Véronique Pellet (Lab. NutriNeuro)

10:30-10:45: Welcome / coffee
10:45-11:10 Shauna Parkes (Post-doc E Coutureau/G Ferreira, INCIA/NutriNeuro, Bordeaux) “Cortico-cortical interactions in food-seeking behaviors”
11:10-11:40 Francis Chaouloff (Neurocentre Magendie, Bordeaux) “The endocannabinoid system sets the desire to exercise?”
11:40-12:05 Arnau Busquets-Garcia (post-doc G Marsicano, Neurocentre Magendie, Bordeaux) "Role of CB1 receptor in odor/taste aversion learning"
12:05-12:30 Quentin Leyrolle (PhD student A Nadjar, NutriNeuro, Bordeaux) “Dietary omega-3 alleviates from long-term behavioral deficits in a model of prenatal infection”.
12:30-13:00 Silvia Lorente (University of Navarra, Pamplona, Spain) "Role of omega-3 fatty acids on inflammatory and degenerative diseases"
13:00-14:00: Lunch
14:05-14:35 Mariano Ruiz-Gayo (Universidad CEU-San Pablo, Madrid, Spain) "Multifactorial influence of high-fat diets on feeding behavior, mood and learning"
14:35-15:00 Celia Fourrier (PhD student N Castanon, NutriNeuro, Bordeaux) "Effects of omega-3/ antioxidant supplemented diet on cognitive alterations associated with obesity".
15:00-15:30 Pedro Gonzalez-Muniesa (University of Navarra, Pamplona, Spain) “The endocannabinoid system, inflammation and obesity”
15:30-15:55 Wilfried Mazier (post-doc D Cota, Neurocentre Magendie, Bordeaux) “Role of mTOR and endocannabinoids in the regulation of hypothalamic melanocortin circuits”




Séminaire
19/02/2016 11h30
Etienne Hirsch

Meeting room: CGFB Seminar room

from ITMO neurosciences's lab will give a presentation entitled 'Unmet therapeutic needs in Parkinson's disease'

Invitant : Gionanni Marsicano, Neurocentre Magendie




Cocaine taking behavior: CB1 receptors in Glu and GABA neurons don’t play the same role.

The endocannabinoid system acts on brain regions involved in reinforcement and addiction to drugs of abuse such as cocaine. The CB1 receptor is the main component of the endocannabinoid system and plays a key role in these processes. So far, however, CB1 receptors have been globally targeted, independent of their localization on specific neuronal populations, including glutamatergic or GABAergic neurons, generating controversial and potentially biased results. Here we demonstrate that the control exercised by CB1 receptors over cocaine taking behavior is differential depending on their localization in glutamatergic or GABAergic neurons. Thus, CB1 receptors in glutamatergic neurons control associative learning through which environmental stimuli gain control over drug seeking while CB1 receptors located on GABAergic neurons control the sensitivity to the primary rewarding effects of the drug.

Differential Control of Cocaine Self-Administration by GABAergic and Glutamatergic CB1 Cannabinoid Receptors.
Martín-García E, Bourgoin L, Cathala A, Kasanetz F, Mondesir M, Gutiérrez-Rodriguez A, Reguero L, Fiancette JF, Grandes P, Spampinato U, Maldonado R, Piazza PV, Marsicano G, Deroche-Gamonet V.  Neuropsychopharmacology. 2015 Nov 27. doi: 10.1038/npp.2015.351. 





Hottopic
25/11/2015 12h00
Carolina Muguruza from Marsicano's lab will give a presentation entitled "Are you motivated to run? The role of Cannabinoid Type 1 (CB1) Receptors."


Focus sur la modulation du comportement par les récepteurs CB1 : l’importance de son profil d’expression

Dissecting the cannabinergic control of behavior: The where matters.
Arnau Busquets-Garcia, Tifany Desprez, Mathilde Metna-Laurent, Luigi Bellocchio, Giovanni Marsicano and Edgar Soria-Gomez
Bioessays. 2015 Aug 11. doi: 10.1002/bies.201500046. [Epub ahead of print]

Group "Endocannabinoids and Neuroadaptation," NeuroCentre Magendie, INSERM U862, Bordeaux Neurocampus, University of Bordeaux, Bordeaux, France.