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Venue: Bordeaux School of Neuroscience

The normal aging process is associated with reduced performance on cognitive tasks that require one to quickly process or transform information to make a decision, including measures of speed of processing, executive cognitive function, working and relational memories. Structural and functional alterations in the brain correlate with these age-related cognitive changes, such as loss of synapses, and dysfunction of neuronal networks. It is crucial to develop new approaches that consider the whole neuroanatomical, endocrine, immunological, vascular and cellular changes impacting on cognition.

This 3-week course will cover the fundamentals of cognitive aging -including inter-individual differences, cognitive and brain reserve and risk factors- and highlight the newest functional imaging methods to study human brain function. The Faculty will share the state-of-the-art molecular, optical, computational, electrophysiological, behavioural and epidemiological approaches available for studying the aging brain in diverse model systems. The Students will learn the potential and limitations of these methods, through practical experience in a combination of lectures addressing aging in both humans and animal models and hands-on-projects. They will acquire sufficient practical experience to model, design and interpret experiments and brainstorm on novel technologies and hypotheses to explore the aging of the brain using more integrative and creative approaches.

Keynote speakers:
Hélène Amieva - University of Bordeaux
Adam Antebi - MPI for Biology of Ageing
Carol Barnes - University of Arizona
LucBuée-Centrede Recherche Jean-Pierre Aubert
Gwenaëlle Catheline - University of Bordeaux
Maria Llorens-Martin - Centro de Biologia
Molecular Severo Ochoa
Aline Marighetto - University of Bordeaux
Lars Nyberg - Umeå University
Laure Rondi-Reig - Sorbonne University
Yaakov Stern - Columbia University
Tony Wyss-Coray - Stanford University

Course director: Luísa Lopes
Co-directors: Cheryl Grady and Nora Abrous

Application deadline: 25 May 2020
Stipends are available

Registration
Fee : 3.500 € (includes tuition fee, accommodation and meals)

The CAJAL programme offers 4 stipends per course (waived registration fee, not including travel expenses). Please apply through the course online application form. In order to identify candidates in real need of a stipend, any grant applicant is encouraged to first request funds from their lab, institution or government.

Kindly note that if you benefited from a Cajal stipend in the past, you are no longer eligible to receive this kind of funding. However other types of funding (such as partial travel grants from sponsors) might be made available after the participants selection process, depending on the course.

For enquiries, please contact: info@cajal-training.org





Actualité de la Société des Neurosciences.https://www.neurosciences.asso.fr/2021/04/les-neurones-generes-a-lage-adulte-dans-lhippocampe-sont-indispensables-au-maintien-de-la-memoire-lors-du-rappel-et-de-sa-mise-a-jour/





Une collaboration entre le GDR et la société Capsule pour le premier podcast Axone.
Nicolas Chavardès, porteur du projet Axone, vous en parle. Construit autour d’un témoignage, Axone revient sur un sujet mis en lumière par des experts. Dans ce premier épisode, nous découvrons la mémoire traumatique.

https://podcast.ausha.co/axone/axone-1-la-memoire-traumatique





La Maison du Cerveau finance 2 stagiaires du Neurocentre Magendie cette année ! Merci pour la confiance de l'association et félicitations pour le travail extraordinaire de ses membres.





Les équipes du Neurocentre Magendie sont porteuses ou partenaires de 4 des 5 "seed projects" retenus par Bordeaux Neurocampus. Bravo aux lauréats!





Memory reconsolidation, the process by which memories are again stabilized after being reactivated, has strengthened the idea that memory stabilization is a highly plastic process. To date, the molecular and cellular bases of reconsolidation have been extensively investigated particularly within the hippocampus. However, the role of adult neurogenesis in memory reconsolidation is unclear. Here, we combined functional imaging, retroviral and chemogenetic approaches in rats to tag and manipulate different populations of rat adult-born neurons. We find that both mature and immature adult-born neurons are activated by remote memory retrieval. However, only specific silencing of the adult-born neurons immature during learning impairs remote memory retrieval-induced reconsolidation. Hence, our findings show that adult-born neurons immature during learning are required for the maintenance and update of remote memory reconsolidation.




Info générale
18/03/2021
Conférence d'Aline Desmedt dans le cadre de la Semaine Du Cerveau

Très beau succès pour la conférence d'Aline Desmedt dans le cadre de la Semaine Du Cerveau. Plus de 110 participants, une séance de questions passionnante...
Malgré la distance, la recherche sur le cerveau attire les citoyens curieux ! Merci à Bordeaux Neurocampus et à la Société des Neurosciences





Cette année la Semaine du Cerveau se consomme sans modération ! Inscrivez-vous ici pour assister à la conférence d'Aline Desmedt sur la mémoire traumatique : https://www.semaineducerveau.fr/manifestation/traiter-la-memoire-traumatique-par-la-contextualisation-du-trauma/





Les membres de la plateforme transcriptome du Neurocentre Magendie partageaient leur expertise avec les élèves du Lycée St Louis la semaine dernière





Congratulations to Nature Metabolism for this excellent recruitment :)