Agenda






Séminaire
07/04/2021 09h00
Steve DOS SANTOS CARVALHO, 3rd Bordeaux Cell Biology Gathering
2021-04-07 09:00:00 2021-04-07 18:00:00 Europe/Paris Steve DOS SANTOS CARVALHO, 3rd Bordeaux Cell Biology Gathering 0    Afficher l'article web Link

Lieu: Agora du Haut Carré, Talence

Rejoignez nous et participez au 3ème BCBG qui aura lieu à Talence (Agora du Haut Carré) le 7 Avril 2020

Programme disponible ici


Pour plus de détails: https://neurocentre-magendie.fr/NCM_Downloads_open/BCBG2020Programme.pdf


Hottopic
30/09/2020 10h00
Marianne AINCY from Herry's lab will give a presentation entitled 'Long-range projecting prefrontal inhibitory neurons control fear expression'
2020-09-30 10:00:00 2020-09-30 10:30:00 Europe/Paris Marianne AINCY 0

Hottopic
30/09/2020 10h30
Céline NICOLAS from Beyeler's lab will give a presentation entitled "Role of insular cortex circuits in a model of alcohol use disorder"
2020-09-30 10:30:00 2020-09-30 11:00:00 Europe/Paris Céline NICOLAS 0

Hottopic
24/06/2020 10h00
Pierre Louis Raux from Revest's lab will give a presentation entitled "Physiological regulation of the cannabinoid type-1 receptor by the neurosteroid pregnenolone: study in mutant CB1-E134G mice"

Hottopic
24/06/2020 10h30
Rafael De Sa from Frick's lab will give a presentation entitled "Single-cell RNA and electrophysiological profiling of D1+ and D2+ principal neurons of the prefrontal cortex"

Hottopic
27/05/2020 10h00
Misa Arizono from Oliet's lab will give a presentation entitled 'Structural basis of astrocytic Ca2+ signals at tripartite synapses'

Hottopic
27/05/2020 10h30
Paula Gomez from Marsicano's lab will give a presentation entitled 'CB1 receptor control of social affective behaviors'

Hottopic
26/02/2020 10h00
Gianluca LAVANCO from Marsicano's lab will give a presentation entitled “What is the role of the mitochondrial CB1 receptor in the cannabinoid-induced modulation of learning and memory and synaptic plasticity?”

Hottopic
26/02/2020 10h30
Jennifer STANIC from Montcouquiol-Sans's lab will give a presentation entitled 'The PSD-95 spatial nano-architecture is altered by Scribble-dependent signaling'

Séminaire
14/02/2020 11h30
Chantal Mathis

Lieu: Neurocentre Magendie Seminar room

from DR2 CNRS, LNCA, Strasbourg's lab will give a presentation entitled 'Early memory deficits appearing during preclinical stages in mouse models of Alzheimer disease'

Invited by Nora Abrous (Neurocentre Magendie)

Abstract

Over the last decade, the main finding about Alzheimer’s disease (AD) is that initial signs have been detected 15 to 20 years before diagnosis (e.g., see Bateman et al, 2012 and Jack et al, 2009). Since then, a great deal of efforts concentrated on the identification of early events and biomarkers that might help us to understand AD pathogenesis. The nature and severity of recognition deficits evolve as AD pathology spreads through medial temporal lobe networks and connected brain structures playing a key role in recognition memories. Therefore, object recognition paradigms have been useful to determine early memory deficits in animal models of AD. The pertinence of behavioral data provided by these paradigms will be analyzed in regard to the neuropathological phenotype of genetically modified rodent models of AD. Our aim is to outline clear advantages and possible limitations in their translational value. We propose that future progress depends on understanding neural networks supporting each form of recognition memory in parallel with the improvement of animal models of AD.