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14/09/2017
Postdoctoral position in Neurophysiology

We are currently searching a highly motivated Postdoctoral researcher with experience in electrophysiology for a project focusing on the study of the role of hypothalamic-mesolimbic neurocircuitry in the development of diet-induced obesity. This project will be jointly carried out in the laboratories of Dr. Daniela Cota (Inserm U1215, Neurocentre Magendie, Bordeaux, France http://www.neurocentre-magendie.fr/cota) and Dr. Xavier Fioramonti (NutriNeuro, INRA UMR 1286, Bordeaux, France, https://www6.bordeaux-aquitaine.inra.fr/nutrineuro ), which both investigate the neurobiological mechanisms of obesity and diabetes. Patch-clamp electrophysiology associated with the use of optogenetics, molecular biology and neuroanatomical analysis are the main approaches that will be used in the project.

Candidates should have a doctoral degree in neuroscience/neurobiology, and recognized expertise in patch-clamp electrophysiology. Previous experience in the study of neuronal circuits involved in the regulation of energy balance using rodent models and in the use of optogenetics coupled with electrophysiology is strongly preferred. Ability to work both independently and cooperatively within a team will be essential.

The project is funded by the Labex Brain (http://brain.labex.u-bordeaux.fr ). The postdoctoral contract will be for a period of 18 months.

Starting date: January 2018

Contact: Candidates should send their CV, motivation letter, list of publications and 2 letters of reference to Dr. Daniela Cota (daniela.cota@inserm.fr) or Dr. Xavier Fioramonti (xavier.fioramonti@inra.fr).





The Cortical Plasticity group at the Neurocentre Magendie (Bordeaux, France) is seeking to recruit a postdoctoral researcher to join their group in Fall 2017

In this project, we are examining the pathophysiological modification of neocortical circuits in different models of autism spectrum disorder. To probe changes in crucial cellular parameters in these transgenic mouse models, we will use a combination of in vitro patch-clamp and two-photon calcium imaging approaches together with single-cell RNA sequencing and pharmacology.

The successful candidate will be initially funded for two years with the possibility of extension. Excellence will be a primary criterion for selection, but experience in electrophysiology and calcium imaging are a bonus. The candidate must have a PhD or equivalent qualification in either neuroscience, life sciences, medicine, or physics. The candidate should also have a good level of proficiency in English.

The team is based at the Neurocentre Magendie, an INSERM research institute, and member of the Bordeaux Neurocampus — a centre of excellence for neuroscience research in France. The day-to-day language is English, but support would be provided for learning French if the candidate so wishes.

For further information, please contact as soon as possible:
Andreas Frick, andreas.frick@inserm.fr

Please see also http://neurocentre-magendie.fr/recherche/Frick/descriptionTeam.php?lang=en

Deadline: 15 July 2017





Offre d’emploi / Job Offer Assistant ingénieur ou ingénieur d’étude (3 à 5 ans d’expérience) Prise de poste : septembre 2016 Durée du contrat : 12 à 18 mois Lieu : Neurocentre Magendie, Bordeaux

Contact : veronique.deroche@inserm.fr
Domaine de recherche : étude expérimentale de l’addiction Compétences théoriques : psychologie expérimentale, neurophysiologie

Compétences expérimentales : tests comportementaux chez le rongeur dont auto-administration intraveineuse, électrophysiologie in vivo (single unit, LFP).

Missions : conduites d’expériences de comportement et d’expériences couplant comportement et électrophysiologie, analyse de données électro-physiologiques.

Requis : formation expérimentation animale niveau 2, chirurgie expérimentale.

Research associate/project engineer (3-5 years of experience) A project engineer/research associate position is available starting on September 2016 in the Neurocentre Magendie, in Bordeaux (France). Length of contract: 12 to 18 months Contact: veronique.deroche@inserm.fr Research domain: experimental studies on addiction We are seeking a talented and highly motivated research associate/project engineer with knowledge in neurophysiology and experimental psychology. The candidate should be technically competent in in vivo electrophysiology (single unit, LFP), and behavioral tests in rodents (including intravenous auto-administration). Research project: Perform behavioral tasks coupled with electrophysiology analysis in behaving rodents, in the context of addiction. Pre-requisite : Training in animal experimentation level 2, experimental surgery




Job offers
02/06/2016
Offre de CDD Développeur intégrateur d’applications informatiques
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La plateforme Bioinformatique recrute un assistant ingénieur de formation Bac+2/+3 Technicien en informatique de maintenance logicielle et matérielle, développeur pour une période de 6 à 7 mois

Compétences requises:
Systèmes d'exploitation Linux (CentOs, Ubuntu)
Langages de programmation: PHP, Python (si possible également Java ou C++)
Bases de données: MySQL
Design Web: HTML5, CSS3, Javascript, Jquery, BootStrap
Niveau en anglais oral apprécié

Qualités
Bon sens relationnel, Rigueur, Autonomie, Sens de l’organisation, Rapidité d'exécution, Sens de l’analyse, Créativité

Missions
Maintenance opérationnelle des serveurs Linux (CentOS) de la plateforme
Assurer la maintenance et assistance matérielle et logicielle des applications existantes
Gérer et maintenir les bases de données MySQL
Programmer tout ou partie de modules sur les logiciels existants
Apporter un soutien technique aux utilisateurs
Mettre à jour les interfaces web des applications
Respect des normes et standards en vigueur.

Merci de contacter le responsable de la plateforme alexandre.brochard@inserm.fr





Job offers
10/05/2016
PhD position in Montcouquiol/Sans lab

A PhD position funded by a French ministerial doctoral contract for 3 years (starting in fall 2016) is available in the group of M. Montcouquiol and N. Sans at the Neurocentre Magendie (NCM) in the Bordeaux Neurocampus, France.

Our interdisciplinary research is focused on neural planar cell polarity (PCP) mechanisms and the transfer of this knowledge into animal models of psychiatric and neuro/developmental diseases (autism, epilepsy, deafness) (Moreau M. et al . J Neurosci 2010; Durand CM et al., Mol Psychiatry 2012; Ezan J. et al. Semin Cell Dev Biol. 2013 ; Piguel NH et al. Cell Reports 2014.). The candidate will study the involvement of a new PCP complex in the establishment and maintenance of neuronal polarity and excitability. Techniques employed include state-of-the-art cell & molecular biology, biochemistry, imaging & high-resolution microscopy.

The successful candidate is highly motivated, hard working and holds a MSc in cell biology, neuroscience, molecular biology, biochemistry or biophysics. We expect a solid background in biochemistry or cell biology. Admission to the program is based on a competitive selection procedure even if the funding for this specific PhD position is already secured. More details available upon request.

The scientific excellence of NCM and its outstanding location in Bordeaux (best European destination 2015) provide a rich and stimulating working/living environment. Applications (CV, motivation letter and experience, at least 1 reference letter) should be sent until May 23 to: jerome.ezan@inserm.fr and nathalie.sans@inserm.fr





Job offers
28/04/2016
Recrutement d’un Ingénieur d’Etude « en Biologie Moléculaire et Cellulaire »

L’équipe « Polarité Planaire et Plasticité » qui vient d’être labélisée Equipe FRM 2016 recrute un ingénieur d’étude en CDD, responsable de son activité de biologie moléculaire et cellulaire.

Mission: l’ingénieur aura en charge la mise en œuvre d’expériences de biologie moléculaire (clonage, mutagénèse, séquençage, etc), de biologie cellulaire (culture cellulaire et transfection pour immunocytochimie et imagerie) et de biochimie des protéines. L’ingénieur aura également en charge la gestion des commandes, des stocks de matériels biologiques et des consommables relatifs aux techniques en question.

Compétences : l’ingénieur aura des connaissances approfondies des différentes techniques utilisées en biologie moléculaire et en biochimie des protéines, ainsi que des connaissances générales des approches méthodologiques appliquées à la biologie et aux neurosciences. L’ingénieur saura concevoir ou développer des protocoles expérimentaux dans le cadre d’un projet scientifique et intégrer son activité dans différents projets. La maîtrise des outils informatiques de recueil et de traitement des données, des techniques de présentations (orales et écrites) et de l’anglais sont importantes.

Contact:
Mireille Montcouquiol et Nathalie Sans, Equipe “Polarité Planaire et Plasticité”, Neurocentre Magendie, Inserm U1215, Université de Bordeaux nathalie.sans@inserm.fr