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Séminaire
20/12/2017 11h30
Freddy Jeanneteau

Lieu: Amphithéatre BROCA

TITRE: Longitudinal two-photon microscopy of the living brain to tackle cellular plasticity.

Static assembly of multiple cell types in the brain is not sustainable when physiological state deviates from homeostasis. Cellular networks must adapt to changes in the environment, aging and disease conditions. What can be learned from the dynamics of cellular networks assembly/disassembly? My lab uses in vivo 2-photon microscopy of the mouse brain to investigate the structural plasticity of cellular networks in normal living conditions and in various pathological states replicating human diseases. I’ll present 2 on-going projects for: (1) tracking the impact of stress on a cortical synaptic engram of motor learning, and (2) for studying the impact of status epilepticus on the remodeling of the blood brain barrier. The results unravel disease mechanisms and have implications for the design of new treatment strategies.




Soutenance de thèse
18/12/2017 14h30
Eva-Gunnel DUCOURNEAU from Marighetto's lab will defend her Ph.D. thesis entitled 'Rôle de la plasticité cellulaire au sein du circuit hippocampo-amygdalien dans la formation d'une mémoire de peur normale ou traumatique'

from Marighetto's lab will defend her Ph.D. thesis entitled 'Rôle de la plasticité cellulaire au sein du circuit hippocampo-amygdalien dans la formation d'une mémoire de peur normale ou traumatique'
Date de la soutenance: 18/12/2017 - 14h30
Lieu: Neurocentre Magendie Seminar room

Pour plus de détails: http://www.bordeaux-neurocampus.fr/fr/formation-doctorale/these-2017/eva-gunnel-ducourneau.html



Dix ans pour mettre au point une gélule qui peut changer la vie de beaucoup d'addicts, une vie qui peut tourner au cauchemar.
C'est un travail d'équipe au long cours qui a ses racines à Bordeaux. Au cours de ses recherches sur les effets du canabis, l'équipe du Neurocentre Magendie a découvert que sa prise entraîne la production dans le cerveau d’une molécule appelée prégnénolone. Elle a pour effet naturel de défendre l’organisme contre les effets de cette drogue. Une solution pour soigner l'addiction au cannabis. Impossible de l'utiliser en tant que telle, elle ne s'y prête pas. Les chercheurs, fédérés autour de Pier-Vincenzo Piazza, directeur de recherche Inserm, ont donc trouver la parade...





Neurocentre Magendie de 9 à 12h30
Valérie Crepel (Inmed, Marseille)
Abnormal synaptic transmission in epilepsy: role of kainate receptors
Fadel Tissir (UCLouvain, Belgique)
Linking genes to brain development and disorders. A focus on corticogenesis
Pierre Trifilieff (NutriNeuro, Bordeaux)
Modulation of dopamine transmission by membrane lipid composition: from receptor signaling to reward processing
Claire Rampon (CRCA, Université Paul Sabatier, Toulouse)
New neurons for old brains : manipulating adult hippocampal neurogenesis in Alzheimer's disease
Olivier Nicole (IMN, Bordeaux)
Cortical switch in the composition of synaptic GluN2-containing NMDA receptors drives the formation of long-lasting associative memory
Aline Desmedt (Neurocentre Magendie, Bordeaux)
PTSD-like memory is associated with specific hippocampal and amygdala neuromorphological alterations





Soutenance de thèse
04/12/2017 14h30
Benjamin Robert Benjamin Robert from the Montcouquiol-Sans' lab will defend his Ph.D. thesis entitled « Rôle de la signalisation de la polarité cellulaire planaire dans les processus mnésiques »

Benjamin Robert from the Montcouquiol-Sans' lab will defend his Ph.D. thesis entitled « Rôle de la signalisation de la polarité cellulaire planaire dans les processus mnésiques »
Date de la soutenance: 04/12/2017 - 14h30
Lieu: Neurocentre Magendie Seminar room

Pour plus de détails: http://www.bordeaux-neurocampus.fr/fr/formation-doctorale/these-2017/benjamin-robert.html



Lieu: Neurocentre Magendie Seminar room

Giovanni Marsicano from Endocannabinoid and Neuroadaptation Group's lab will give the PhD seminar series December entitled 'Cannabinoid CB1 receptor signaling in the brain: the where matters'.

Invitant : Bordeaux Neurocampus / NBA

Abstract :
Cannabinoid drugs (e.g. the active principle of the plant cannabis, D9-tetrahydrocannabinol, THC) exert several effects on the brain via the activation of the G protein-coupled type-1 cannabinoid receptors (CB1).




Pour plus de détails: http://www.bordeaux-neurocampus.fr/fr/manifestations-scientifiques/seminaires-2017/giovanni-marsicano.html


Info générale
28/09/2017
Neurocampus en tête
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Pleine page dans Sud-Ouest pour se remémorer les détails du projet Neurocampus.




Offre de poste
26/09/2017
Postdoctoral position in Neurobiology of obesity and diabetes

We are searching a highly motivated Postdoctoral researcher to join the research team led by Dr. Daniela Cota at the Inserm Unit 1215, Neurocentre Magendie (http://www.neurocentre-magendie.fr/cota) in Bordeaux, France.
The research focus of the team is the study of the neurobiology of obesity and diabetes. The project that the successful candidate will carry out aims at determining how nutrient-sensing mechanisms related to bile acids act within the hypothalamus and define their role in diet-induced obesity. Use of stereotaxic surgery and chemogenetics, associated with in vivo behavioral and metabolic assessments coupled with molecular biology and neuroanatomical analysis are the main approaches required.
Candidates should have a doctoral degree in neuroscience/neurobiology/nutrition/metabolism. Previous experience in the study of hypothalamic neuronal circuits involved in the regulation of energy balance and metabolism using rodent models is strongly preferred. Ability to work both independently and cooperatively within a team is essential.
The appointment is for 30 months. The position is available starting January 2018 and is funded by the ANR.
Candidates should send their CV, motivation letter, list of publications and 2 letters of reference to Dr. Daniela Cota (daniela.cota@inserm.fr).




Soutenance de thèse
22/09/2017 14h30
Maria Isabel Carreno-Munoz from Frick's lab will defend her thesis entitled "Supervised and unsupervised investigation of the temporal dynamics of normal and pathological behaviour in the mouse and rat"

from Frick's lab will defend her thesis entitled "Supervised and unsupervised investigation of the temporal dynamics of normal and pathological behaviour in the mouse and rat"
Date de la soutenance: 22/09/2017 - 14h30
Lieu: CGFB Seminar room

Pour plus de détails: http://www.bordeaux-neurocampus.fr/fr/formation-doctorale/these-2017/these-maria-isabel-carreno-munoz.html



The laboratory of Neuronal Circuits of Associative Learning at the University of Bordeaux, Neurocenter Magendie (INSERM U1215), France (https://www.neurocentre-magendie.fr), is seeking an enthusiastic, highly motivated postdoctoral researcher to join our team dedicated to identifying the neuronal circuits mediating fear behavior. Our main focus is to identify the neuronal circuits, mechanisms and coding scheme of active and passive fear reactions using state of the art in vivo recordings approaches coupled to optogenetic and behavioral manipulations.
The candidate should have a strong motivation to succeed in science as well as excellent organizational and communication skills. Experience with in vivo single unit recordings and/or in vivo imaging and signal analyses is very welcome. Qualified applicants should hold a Ph.D. in Neuroscience or related field.
Candidates should submit their CV and a one page cover letter outlining their research interests, along with contact information for at least two references, to Dr. Cyril Herry (cyril.herry@inserm.fr). Review of applications will start immediately and continue until the position is filled.