Aelis Farma, une start-up de la région de Bordeaux, est en train de développer un traitement inédit et potentiellement très efficace contre l’addiction au cannabis.
Et elle a réussi à lever plus de 1,5 million d’euros en 2013 auquel viennent s’ajouter des prêts et des aides publiques pour un montant de 2,5 millions.
Les raisons de ce succès : la mise au point d’un type totalement nouveau de médicament qui pourrait permettre de soigner d’autres maladies.

from Marsicano's lab will defend her thesis entitled 'Role(s) of mitochondrial type-1 cannabinoid receptors in the brain'
Date de la soutenance: 13/05/2015 - 14h00
Lieu: CGFB Seminar room

Pour plus de détails: http://www.bordeaux-neurocampus.fr/fr/formation-doctorale/theses-2015/tifany-desprez.html

Organisateurs : Nathalie Sans (Neurocentre) & Maurice Garret (INCIA)

speakers de Magendie:
- Aude Panatier
- Guillaume Bony

Lieu: CGFB

, Schild Professor of Pharmacology and HoD, will give a presentation entitled 'Axe Synapse'.

Invitant : Nathalie Sans, Maurice Garret


Pour plus de détails: http://www.bordeaux-neurocampus.fr/fr/manifestations-scientifiques/seminaires-fbn-2015/tina-bashford.html

Lieu: Neurocentre Magendie Seminar room

will give a presentation entitled 'Adolescent cannabinoid exposure and psychosis: further insight into the molecular underpinnings'.

Invitant : Stéphanie Callé-Garnier, INCIA


Pour plus de détails: http://www.bordeaux-neurocampus.fr/fr/manifestations-scientifiques/seminaires-fbn-2015/tiziana-rubino.html

Lieu: Neurocentre Magendie Seminar room

"Implications of gabaergic miswiring on brain function: role of Nrg/Erbb4 signaling in interneuron development".

Invited by Andreas Frick

Abstract: Inhibitory cells are essential to fine-tuning the activity of neural circuits. Different classes of interneurons target distinct subcellular compartments of the pyramidal cell. This suggests that there is a differential contribution of each subtype of interneuron in the regulation of the network. In particular, cholecystokinin (CCK) expressing interneurons differ in chemical features and their postsynaptic targets, yet the role of each of these subtypes in the regulation of neuronal network activity is poorly understood. In this study, we describe a subpopulation of CCK interneurons co-expressing the vesicular glutamate transporter 3 (VGlut3) that also shows tyrosine kinase ErbB4 receptor expression. These interneurons are mainly basket cells targeting both, pyramidal cells and Parvalbumin-expressing interneurons in the hippocampus. To address the role of CCK-VGlut3 interneurons in network activity regulation, we combined mouse genetics with a set of different experimental approaches. Our results suggest that specific conditional deletion of ErbB4 receptor from CCK-expressing cells, results in deficient VGlut3 innervation. In addition, abnormal wiring of CCK-VGlut3 expressing interneurons perturbs cortical oscillatory activity as well as spatial representation in vivo and leads to specific behavioural deficits.