Agenda & Actualités

06/05/2011 12h00
Julien COURTIN Julien COURTIN from Piazza's lab will present his project entitled 'A subpopulation of prefrontal putative inhibitory interneurons controls conditioned fear expression'. Accumulating evidence indicate that the medial prefrontal cortex is necessary for conditioned fear expression. It is likely that neuronal changes occurring during fear expression depends on specific interactions between excitatory and inhibitory prefrontal microcircuits. However such microcircuits are still unknown. Recent anatomical and electrophysiological data indicate that cortical inhibitory circuits might regulate pyramidal cell activity at multiple levels. In order to evaluate the role of inhibitory prefrontal microcircuits during expression of conditioned fear responses we used single units recordings in behaving animals submitted to auditory fear conditioning. We found that a subpopulation of prefrontal putative inhibitory interneurons might selectively control conditioned fear expression.

Federico Massa accorde une interview à Yves Deris à l'occasion de sa publication dans PNAS.

29/04/2011 12h00
Matthias HABERL Matthias HABERL from Frick's lab will present his project entitled 'Neocortical circuitry in a model of mental retardation' The function of cortical circuits emerges from its anatomical wiring diagram and wiring defects are probably involved in a manyfold of neurological diseases. Still the detailed organization of the mammalian neocortex remains largely unknown and exceedingly difficult to investigate. Therefore cutting-edge tools that allow us to dissect the sub-circuits are inevitable. To study connectivity in the neocortex we are using viral tracing techniques, as lentivirus and rabies-based monosynaptic trans-synaptic tracing. We look at changes of connectivity in mental retardation, from fine scale microcircuits up to long ranging projections from the entire brain. We hope not just to learn more about importance of specific circuits in normal and diseased (Fragile X Syndrome) brain but also to understand more about the involvement of wiring defects in neurological diseases in general.

26/04/2011 12h00
David DiGregorio

Lieu: Seminar room

Vous êtes tous cordialement invités, étudiants, chercheurs, universitaires à assister à cette conférence de David DiGregorio
'Spatio-temporal filtering of information flow by sublinear synaptic integration within thin dendrites' à l'Institut Magendie.

Pour plus de détails :
Une invitation de Valentin Nagerl

22/04/2011 12h00
Yu ZHANG Yu ZHANG from Frick's lab will present his project entitled 'Pathophysiology of information processing in neocortical dendrites in Fragile X Syndrome' Fragile X Syndrome (FXS) is the most common form of inherited mental retardation syndrome, and it is caused by a silencing mutation of the gene Fmr1 (encoding the protein FMRP). In humans, the consequences of this disorder include hypersensitivity to sensory stimuli, autistic behavior, seizures, and learning and memory deficits. Channelopathies have not been addressed as a prominent feature of FXS, although several ion channel subunits are amongst the genes whose mRNAs are regulated by FMRP. These channels strongly regulate the active properties of dendrites and therefore dendritic information processing. We will probe ion channel dysfunction and its consequences for dendritic function in layer 5B pyramidal neurons of the whisker-related barrel cortex.

15/04/2011 12h00
Isabelle MATIAS Isabelle MATIAS from Marsicano's lab will present his project entitled 'Simultaneous Post-prandial Deregulation of the Orexigenic Endocannabinoid Anandamide and the Anorexigenic Peptide YY in Obesity'

14/04/2011 14h00
Michel Rouxel, Ingenieur Commercial, Beckman Coulter France

Lieu: Seminar room

Séminaire de 45 minutes sur : 'Les bonnes pratiques de la centrifugation' de Michel Rouxel, Ingenieur Commercial, Beckman Coulter France.
Entrée libre , organisation Nathalie Sans.

11/04/2011 12h00
Andrea Green

Lieu: Seminar room

Vous êtes tous cordialement invités, étudiants, chercheurs, universitaires à assister à cette conférence
'Neural computations for estimating self-motion'
Une invitation de Thomas Boraud de l'IMN.

Plus de détails :

- Eteignez l'ordinateur ou mettez-le en veille votre ordinateur lorsque vous ne l'utilisez pas
- Eteignez l'écran lorsque vous laissez temporairement votre ordinateur.
- Evitez les économiseurs d'écrans qui empêchent la mise en veille de l'écran.
- Eteignez vos hauts parleurs lorsque ceux-ci ne fonctionnent pas.
- Eteignez votre imprimante entre chaque session d'impression.
- Une prise multiple à interrupteur permet de débrancher facilement l'ensemble de votre matériel.

04/04/2011 10h00
Fernando Kasanetz - Christelle Durand

Lieu: Seminar room

9ème Journée Scientifique 'Synapse' - 9th Synapse Day Meeting