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07/04/2021 09h00
Steve DOS SANTOS CARVALHO, 3rd Bordeaux Cell Biology Gathering
2021-04-07 09:00:00 2021-04-07 18:00:00 Europe/Paris Steve DOS SANTOS CARVALHO, 3rd Bordeaux Cell Biology Gathering 0    Show the web article Link

Lieu: Agora du Haut Carré, Talence

Join us and participate in the third BCBG meeting occuring at Talence (Agora Du Haut Carré) on April the 7th of 2020.

Program available here

Pour plus de détails:

General informations
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Venue: Bordeaux School of Neuroscience

The normal aging process is associated with reduced performance on cognitive tasks that require one to quickly process or transform information to make a decision, including measures of speed of processing, executive cognitive function, working and relational memories. Structural and functional alterations in the brain correlate with these age-related cognitive changes, such as loss of synapses, and dysfunction of neuronal networks. It is crucial to develop new approaches that consider the whole neuroanatomical, endocrine, immunological, vascular and cellular changes impacting on cognition.

This 3-week course will cover the fundamentals of cognitive aging -including inter-individual differences, cognitive and brain reserve and risk factors- and highlight the newest functional imaging methods to study human brain function. The Faculty will share the state-of-the-art molecular, optical, computational, electrophysiological, behavioural and epidemiological approaches available for studying the aging brain in diverse model systems. The Students will learn the potential and limitations of these methods, through practical experience in a combination of lectures addressing aging in both humans and animal models and hands-on-projects. They will acquire sufficient practical experience to model, design and interpret experiments and brainstorm on novel technologies and hypotheses to explore the aging of the brain using more integrative and creative approaches.

Keynote speakers:
Hélène Amieva - University of Bordeaux
Adam Antebi - MPI for Biology of Ageing
Carol Barnes - University of Arizona
LucBuée-Centrede Recherche Jean-Pierre Aubert
Gwenaëlle Catheline - University of Bordeaux
Maria Llorens-Martin - Centro de Biologia
Molecular Severo Ochoa
Aline Marighetto - University of Bordeaux
Lars Nyberg - Umeå University
Laure Rondi-Reig - Sorbonne University
Yaakov Stern - Columbia University
Tony Wyss-Coray - Stanford University

Course director: Luísa Lopes
Co-directors: Cheryl Grady and Nora Abrous

Application deadline: 25 May 2020
Stipends are available

Fee : 3.500 € (includes tuition fee, accommodation and meals)

The CAJAL programme offers 4 stipends per course (waived registration fee, not including travel expenses). Please apply through the course online application form. In order to identify candidates in real need of a stipend, any grant applicant is encouraged to first request funds from their lab, institution or government.

Kindly note that if you benefited from a Cajal stipend in the past, you are no longer eligible to receive this kind of funding. However other types of funding (such as partial travel grants from sponsors) might be made available after the participants selection process, depending on the course.

For enquiries, please contact:

24/06/2020 10h00
Pierre Louis Raux from Revest's lab will give a presentation entitled "Physiological regulation of the cannabinoid type-1 receptor by the neurosteroid pregnenolone: study in mutant CB1-E134G mice"

24/06/2020 10h30
Rafael De Sa from Frick's lab will give a presentation entitled "Single-cell RNA and electrophysiological profiling of D1+ and D2+ principal neurons of the prefrontal cortex"

Ignacio Fernandez Moncada was born far away, in the colorful city of Valparaiso (Chili), that faces the Pacific Ocean. He is now a post-doc researcher at the Neurocentre Magendie, in Giovanni Marsicano’s team. Let’s meet him!

27/05/2020 10h00
Misa Arizono from Oliet's lab will give a presentation entitled 'Structural basis of astrocytic Ca2+ signals at tripartite synapses'

27/05/2020 10h30
Paula Gomez from Marsicano's lab will give a presentation entitled 'CB1 receptor control of social affective behaviors'

Scientists from the Laboratory of Neurodegenerative Diseases (CNRS/CEA/University of Paris-Saclay) and the Neurocentre Magendie (Inserm/University of Bordeaux) have just highlighted the decisive role played by a metabolic pathway in memory impairment in Alzheimer's disease. Their work, to be published on 3 March 2020 in Cell Metabolism, also shows that a particular amino acid intake, in the form of a dietary supplement, restores the spatial memory affected early in mice models of the disease. This is a promising avenue for alleviating Alzheimer's-related memory loss.

Impairment of Glycolysis-Derived L-Serine Production in Astrocytes Contributes to Cognitive Deficits in Alzheimer’s Disease. Juliette Le Douce, Marianne Maugard, Julien Veran, Marco Matos, Pierrick Jégo, Pierre-Antoine Vigneron, Emilie Faivre, Xavier Toussay,Michel Vandenberghe, Yaël Balbastre, Juliette Piquet, Elvire Guiot, Nguyet Thuy Tran, Myriam Taverna, Stéphane Marinesco, Ayumi Koyanagi, Shigeki Furuya, Mylène Gaudin-Guerif, Sébastien Goutal, Aurélie Ghettas, Alain Pruvost, Alexis-Pierre Bemelmans, Marie-Claude Gaillard, Karine Cambon, Lev Stimmer, Véronique Sazdovitch, Charles Duyckaerts, Graham Knott, Anne-Sophie Hérard, Thierry Delzescaux, Philippe Hantraye, Emmanuel Brouillet, Bruno Cauli, Stéphane H.R. Oliet, Aude Panatier et Gilles Bonvento. Cell Metabolism, le 3 mars 2020. DOI : 10.1016/j.cmet.2020.02.004

26/02/2020 10h00
Gianluca LAVANCO from Marsicano's lab will give a presentation entitled “What is the role of the mitochondrial CB1 receptor in the cannabinoid-induced modulation of learning and memory and synaptic plasticity?”