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From discrepancy to paradox through optogenetic: Inactivation of the Prelimbic cortex can indeed inhibit and promote cocaine seeking. - See more at: http://www.neuroscience.univ-bordeauxsegalen.fr/fr/publications/highlights/deroche-npph2014.html#sthash.4PfEGUCt.dpuf




General informations
01/04/2014
Annual meeting Optopath - Tuesday 1st April 2014 - 2 PM
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Neurocentre Magendie - Salle de conférence




General informations
13/03/2014
Neurosciences conference 'Memory'
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Veuillez noter la prochaine conférence-débat sur les Neurosciences qui aura lieu le jeudi 13 mars 2014 (18h30), dans l'Auditorium de la médiathèque Jacques Ellul à Pessac (voir affiche en annexe).

Le thème de ce 3ème rendez-vous sera "La mémoire", sujet développé par les deux intervenants Jean-François Dartigues(1) et Aline Desmedt(2).
Le débat sera animé par Didier Dubrana, chargé de communication Inserm - Aquitaine, Poitou-Charentes

Cette conférence est destinée au grand public, elle est gratuite.
Le contact est : biblio.adultes@mairie-pessac.fr

NB :
(1) Jean-François Dartigues est professeur des Universités - Praticien-hospitalier en épidémiologie, économie de la santé et prévention
(2) Aline Desmedt est maître de conférences - Enseignante-chercheure à l'unité Inserm U862, Physiopathologie de la plasticité neuronale.





La date de naissance d'un neurone détermine sa fonction dans la mémoire

Influence of ontogenetic age on the role of dentate granule neurons. Tronel S, Lemaire V, Charrier V, Montaron MF, Abrous DN. Brain Struct Funct. 2014 Feb 9. ;

See more here





Gliotransmission: the point with the best scientists of the question





A collaboration between experts of neurosecretion and experts of neuronal rhythms shows the importance of tempo in the reproduction. February 2014




Press review
10/02/2014
Hippocampal neurogenesis
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Neuroscientist Dr Nora Abrous is leading a team of researchers in
the quest to further knowledge of the neuronal basis of memory. The
group has already uncovered novel findings surrounding the role and
importance of generating new adult neurons in the hippocampus

International Innovation, published by Research Media, is the leading global dissemination resource for the wider scientific, technology and research communities, dedicated to disseminating the latest science, research and technological innovations on a global level. More information and a complimentary subscription offer to the publication can be found at: www.researchmedia.eu.






Experiments are conducted on the impact in the brain tetrahydrocannabinol, one of the cabannis active derivatives, by researchers at the laboratory Inserm in Bordeaux (Gironde)





Pregnenolone can protect the brain from cannabis intoxication.
Vallée M, Vitiello S, Bellocchio L, Hébert-Chatelain E, Monlezun S, Martin-Garcia E, Kasanetz F, Baillie GL, Panin F, Cathala A, Roullot-Lacarrière V, Fabre S, Hurst DP, Lynch DL, Shore DM, Deroche-Gamonet V, Spampinato U, Revest JM, Maldonado R, Reggio PH, Ross RA, Marsicano G, Piazza PV.
Science. 2014 Jan 3;343(6166):94-8. doi: 10.1126/science.1243985





Two teams of researchers from Inserm " have discovered that a molecule [ pregnenolone ] produced by the brain was a natural defense mechanism against the harmful effects of cannabis ," reported AFP and France Info . With high doses of cannabis administered to rats and mice , the researchers were able to " increase the cerebral concentration of pregnenolone in the brain and block the harmful effects of the active ingredient of cannabis ( THC ), which acts on receptors cannabinoid (CB1 ) on neurons , "said the news agency . Pier Vincenzo Piazza, who led the study , said that the intakes were " on the order of 3 to 10 times more " than those which are exposed to regular cannabis users . The researcher explains that he developed derivatives of pregnenolone "modified so that it can be absorbed by the body and does not evolve into steroid hormones ." Hope and add " to begin clinical trials on humans in a year to a year and a half at least ." According to him, if the effectiveness of derivatives was confirmed, it would be the "first pharmacological therapy of cannabis dependence ."

AFP , France Info, 02/01