News & Events









Ignacio Fernandez Moncada was born far away, in the colorful city of Valparaiso (Chili), that faces the Pacific Ocean. He is now a post-doc researcher at the Neurocentre Magendie, in Giovanni Marsicano’s team. Let’s meet him!




Hottopic
27/05/2020 10h00
Misa Arizono from Oliet's lab will give a presentation entitled 'Structural basis of astrocytic Ca2+ signals at tripartite synapses'

Hottopic
27/05/2020 10h30
Paula Gomez from Marsicano's lab will give a presentation entitled 'CB1 receptor control of social affective behaviors'




Scientists from the Laboratory of Neurodegenerative Diseases (CNRS/CEA/University of Paris-Saclay) and the Neurocentre Magendie (Inserm/University of Bordeaux) have just highlighted the decisive role played by a metabolic pathway in memory impairment in Alzheimer's disease. Their work, to be published on 3 March 2020 in Cell Metabolism, also shows that a particular amino acid intake, in the form of a dietary supplement, restores the spatial memory affected early in mice models of the disease. This is a promising avenue for alleviating Alzheimer's-related memory loss.


Impairment of Glycolysis-Derived L-Serine Production in Astrocytes Contributes to Cognitive Deficits in Alzheimer’s Disease. Juliette Le Douce, Marianne Maugard, Julien Veran, Marco Matos, Pierrick Jégo, Pierre-Antoine Vigneron, Emilie Faivre, Xavier Toussay,Michel Vandenberghe, Yaël Balbastre, Juliette Piquet, Elvire Guiot, Nguyet Thuy Tran, Myriam Taverna, Stéphane Marinesco, Ayumi Koyanagi, Shigeki Furuya, Mylène Gaudin-Guerif, Sébastien Goutal, Aurélie Ghettas, Alain Pruvost, Alexis-Pierre Bemelmans, Marie-Claude Gaillard, Karine Cambon, Lev Stimmer, Véronique Sazdovitch, Charles Duyckaerts, Graham Knott, Anne-Sophie Hérard, Thierry Delzescaux, Philippe Hantraye, Emmanuel Brouillet, Bruno Cauli, Stéphane H.R. Oliet, Aude Panatier et Gilles Bonvento. Cell Metabolism, le 3 mars 2020. DOI : 10.1016/j.cmet.2020.02.004
https://www.cell.com/cell-metabolism/fulltext/S1550-4131(20)30063-2




Hottopic
26/02/2020 10h00
Gianluca LAVANCO from Marsicano's lab will give a presentation entitled “What is the role of the mitochondrial CB1 receptor in the cannabinoid-induced modulation of learning and memory and synaptic plasticity?”

Hottopic
26/02/2020 10h30
Jennifer STANIC from Montcouquiol-Sans's lab will give a presentation entitled 'The PSD-95 spatial nano-architecture is altered by Scribble-dependent signaling'