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Lieu: Amphi Broca

Principal Investigator, Momentum Laboratory of Molecular Neurobiology,Budapest , Hungary, Hungarian Academy of Sciences - Synaptic junctions are major sites of communication in the brain, where chemical messenger molecules transmit information from presynaptic neurons to their postsynaptic partners.The efficacy of synaptic transmission is not constant in time and space. Instead, its plasticity is a fundamental phenomenon underlying information storage and adaptation to environmental stimuli. Although classical neurotransmitters (such as glutamate and GABA) have well characterized principal roles in mediating basal neurotransmission, emerging evidence has revealed that synapses exploit a plethora of additional messenger molecules integrated into sophisticated signaling pathways to accomplish their complex functions. Thus, the major objective of our laboratory is to identify new signaling systems regulating synaptic transmission and its plasticity. We aspire to delineate the molecular architecture of these novel pathways and to elucidate their physiological roles. Ultimately, this activity is envisaged to help gain a better understanding of synaptic function and reveal new aspects of impaired synaptic activity in brain disorders.


Pour plus de détails: http://www.bordeaux-neurocampus.fr/fr/manifestations-scientifiques/seminaires-2019/istvan-katona.html


Seminars
11/01/2019 11h30
Stefano Palminteri invited by Véronique Deroche-Gamonet
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Lieu: Amphi CGFB

Humans are biased reinforcement learners: evidence from behavioural and neural data

Abstract : The goal of a reinforcement learner is learning what to do so as to maximize future expected reward. A prerequisite to achieve this goal is to learn a action value function, that is an internal estimation of the future expected reward following a given action. In this talk I will present behavioural and neural evidence that humas do not learn this action value function in an objective manner.




Pour plus de détails: http://www.bordeaux-neurocampus.fr/fr/manifestations-scientifiques/seminaires-2019/stefano-palminteri.html


Hottopic
19/12/2018 10h00
Ignacio FERNANDEZ MONCADA from Marsicano's lab will give a presentation entitled "A cannabinoid link between astroglial bioenergetics and brain function?"

Hottopic
19/12/2018 10h30
Sebastien DELCASSO from Beyeler's lab will give a presentation entitled "Anatomical and functional organization of valence circuits in the insular cortex."


General informations
14/12/2018
Demo PrestoCHILL/FlashFREEZE Microm
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This system allows a quick freezing and/or coating of the samples without isopentane and nitrogen, this dmo will take place on Friday 14/12 from 9h30 to 11h30 on the first tage in front of the caftria.




PhD/HDR defense
14/12/2018 14h00
Geoffrey TERRAL - Roles of cannabinoid type-1 receptors in the anterior piriform cortex

- Roles of cannabinoid type-1 receptors in the anterior piriform cortex

Being involved in many behavioral functions, olfaction has powerful influence in guiding our actions. Odors communicate with the central nervous system via specialized receptors in the nose olfactory epithelium that generate neuronal signals, which in turn are eventually distributed and processed in many brain regions. In particular, the anterior piriform cortex (aPC) is an important olfactory area involved in perception and integration of odors. Given the extended role of the main cannabinoid type-1 (CB1) receptor in sensory and memory brain functions, we hypothesized that CB1 receptors could modulate odor processing in the aPC. To this aim, using a combination of anatomical, electrophysiological, and pharmacological approaches, we first characterized the distribution of CB1 receptors and their ability to regulate aPC circuits. We found that CB1 receptors are mainly expressed in GABAergic interneurons where their activation regulates inhibitory transmission and plasticity. Then, we evaluated the role and the impact of CB1 receptor modulation on odor-related aPC processing. In vivo calcium imaging revealed that odor-evoked aPC activity is affected by alteration of CB1 receptor signaling. Additionally, we demonstrated that physiological aPC-CB1 receptors functioning is necessary for retrieve appetitive but not aversive olfactory memory, likely through modulation of local inhibitory circuits. Overall, this work contribute to a better understanding of how CB1 receptors modulate olfactory processes in the aPC.

Date de la soutenance: 14/12/2018 - 14h00
Lieu: Neurocentre Magendie Seminar room

Pour plus de détails: http://www.bordeaux-neurocampus.fr/fr/formation-doctorale/archives-des-theses/theses-2018/geoffrey-terral.html


Seminars
13/12/2018 10h00
Olfaction Symposium - organized by Guillaume Ferreira, Lisa Roux & Giovanni Marsicano
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Lieu: Neurocentre Magendie Seminar Room

Olfaction has long been considered as a « secondary » sensory modality but recent discoveries highlighted its central role in brain functions. During the first session of this symposium, the neurobiological bases of olfactory learning from the early stages of life (Coureaud, Sullivan) to adulthood (Busquets-Garcia, Nicole) will be illustrated. The second session will primarily focus on the physiology of the first relays of olfactory information processing, namely the olfactory bulb and the piriform cortex (or homologous structures in Drosophila), as well as their strong interactions (Nissant, Plaçais, Martin and Wilson)


Pour plus de détails: http://www.bordeaux-neurocampus.fr/fr/manifestations-scientifiques/seminaires-2018/symposium-olfaction.html


General informations
10/12/2018
Promotion !

Congratulations Claire Leger (Oliet team) who is promoted to the TS grade at the University of Bordeaux.




PhD/HDR defense
07/12/2018 14h00
Vernon Garcia-Rivas from Deroche's lab will defend his PhD thesis entitled "Psychobiological correlates of individual variations in the control of nicotine seeking by nicotine and nicotine-associated cues".

from Deroche's lab will defend his PhD thesis entitled "Psychobiological correlates of individual variations in the control of nicotine seeking by nicotine and nicotine-associated cues".
Date de la soutenance: 07/12/2018 - 14h00
Lieu: Neurocentre Magendie Seminar room